Recent advances in biosensing for neurotransmitters and disease biomarkers using microelectrodes

Shaneel Chandra, Shajahan Siraj, Danny K. Y. Wong

    Research output: Contribution to journalReview articlepeer-review

    13 Citations (Scopus)

    Abstract

    This Minireview focuses on recent advances in the applications of microelectrodes to detect and monitor targeted analytes in bioelectrochemical processes. Notably, these processes are electrochemically driven reactions that involve the detection of targets from the biological realm. Wide-ranging applications of electrochemical sensors have been reported in the last few decades in various research fields, owing to favorable attributes such as high selectivity and sensitivity, rapid analysis, simplicity, easy fabrication, and cost effectiveness. Accordingly, in this Minireview, we explore recent advances in bioelectrochemistry based on small detection probes or structures modified for a variety of analytes, exploiting multi-approach advantages of enhanced electrochemical detection surface or targeted analyte pursuit. The target analytes included in this Minireview are neurotransmitters and disease biomarkers detected using enzymatic and non-enzymatic electrode modifications.

    Original languageEnglish
    Pages (from-to)822-833
    Number of pages12
    JournalChemElectroChem
    Volume4
    Issue number4
    DOIs
    Publication statusPublished - 2017

    Keywords

    • electrochemical biosensing
    • electrode arrays
    • neurotransmitter detection
    • disease biomarker detection
    • modified microelectrodes

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