Recent advances in liposome formulations for breast cancer therapeutics

Biyao Yang, Bo-ping Song, Shaina Shankar, Anna Guller, Wei Deng*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Among many nanoparticle-based delivery platforms, liposomes have been particularly successful with many formulations passed into clinical applications. They are well-established and effective gene and/or drug delivery systems, widely used in cancer therapy including breast cancer. In this review we discuss liposome design with the targeting feature and triggering functions. We also summarise the recent progress (since 2014) in liposome-based therapeutics for breast cancer including chemotherapy and gene therapy. We finally identify some challenges on the liposome technology development for the future clinical translation.

Original languageEnglish
Pages (from-to)5225-5243
Number of pages19
JournalCellular and Molecular Life Sciences
Volume78
Issue number13
Early online date11 May 2021
DOIs
Publication statusPublished - Jul 2021
Externally publishedYes

Keywords

  • Breast cancer
  • Cancer therapy
  • Liposomal delivery
  • Triggerable liposomes

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