Abstract
Among many nanoparticle-based delivery platforms, liposomes have been particularly successful with many formulations passed into clinical applications. They are well-established and effective gene and/or drug delivery systems, widely used in cancer therapy including breast cancer. In this review we discuss liposome design with the targeting feature and triggering functions. We also summarise the recent progress (since 2014) in liposome-based therapeutics for breast cancer including chemotherapy and gene therapy. We finally identify some challenges on the liposome technology development for the future clinical translation.
Original language | English |
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Pages (from-to) | 5225-5243 |
Number of pages | 19 |
Journal | Cellular and Molecular Life Sciences |
Volume | 78 |
Issue number | 13 |
Early online date | 11 May 2021 |
DOIs | |
Publication status | Published - Jul 2021 |
Externally published | Yes |
Keywords
- Breast cancer
- Cancer therapy
- Liposomal delivery
- Triggerable liposomes