TY - JOUR
T1 - Recent advances in understanding the influence of composite-formulation properties on the performance of dry powder inhalers
AU - Young, Paul M.
AU - Traini, Daniela
AU - Coates, Matthew
AU - Chan, Hak-Kim
PY - 2007/5
Y1 - 2007/5
N2 - The aerosolisation performances of dry powder inhaler (DPI) systems have been concisely reviewed, focusing on the composite interactions that exist in this kind of complex systems between cohesive and adhesive forces. Furthermore, the influence of the inhalation device design on the performance of the powder formulation has been evaluated. In summary, how the specific properties of formulation components are directly linked to aerosolisation performance of DPI systems is highlighted in this article.
AB - The aerosolisation performances of dry powder inhaler (DPI) systems have been concisely reviewed, focusing on the composite interactions that exist in this kind of complex systems between cohesive and adhesive forces. Furthermore, the influence of the inhalation device design on the performance of the powder formulation has been evaluated. In summary, how the specific properties of formulation components are directly linked to aerosolisation performance of DPI systems is highlighted in this article.
KW - Dry powder inhalation
KW - Aerosol
KW - Engineered composites
KW - Active pharmaceutical ingredient
UR - http://www.scopus.com/inward/record.url?scp=34247373111&partnerID=8YFLogxK
U2 - 10.1016/j.physb.2006.12.058
DO - 10.1016/j.physb.2006.12.058
M3 - Article
SN - 0921-4526
VL - 394
SP - 315
EP - 319
JO - Physica B: Condensed Matter
JF - Physica B: Condensed Matter
IS - 2
ER -