Recent insights for the emerging COVID-19: drug discovery, therapeutic options and vaccine development

Yuefei Zhu, Jia Li, Zhiqing Pang

    Research output: Contribution to journalReview articlepeer-review

    47 Citations (Scopus)
    173 Downloads (Pure)

    Abstract

    SARS-CoV-2 has been marked as a highly pathogenic coronavirus of COVID-19 disease into the human population, causing over 5.5 million confirmed cases worldwide. As COVID-19 has posed a global threat with significant human casualties and severe economic losses, there is a pressing demand to further understand the current situation and develop rational strategies to contain the drastic spread of the virus. Although there are no specific antiviral therapies that have proven effective in randomized clinical trials, currently, the rapid detection technology along with several promising therapeutics for COVID-19 have mitigated its drastic transmission. Besides, global institutions and corporations have commenced to parse out effective vaccines for the prevention of COVID-19. Herein, the present review will give exhaustive details of extensive researches concerning the drug discovery and therapeutic options for COVID-19 as well as some insightful discussions of the status of COVID-19.

    Original languageEnglish
    Pages (from-to)4-23
    Number of pages20
    JournalAsian Journal of Pharmaceutical Sciences
    Volume16
    Issue number1
    Early online date4 Jul 2020
    DOIs
    Publication statusPublished - Jan 2021

    Bibliographical note

    Copyright 2020 Shenyang Pharmaceutical University. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

    Keywords

    • Coronavirus
    • COVID-19
    • Drug discovery
    • Precise prevention and control
    • SARS-CoV-2
    • Vaccine development

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