TY - JOUR
T1 - Recent progress in upconversion luminescence nanomaterials for biomedical applications
AU - Duan, Chengchen
AU - Liang, Liuen
AU - Li, Li
AU - Zhang, Run
AU - Xu, Zhi Ping
PY - 2018/1/14
Y1 - 2018/1/14
N2 - Upconversion nanoparticles (UCNPs) are one kind of luminescence nanomaterials that convert low energy photons to high energy emissions. These nanomaterials have recently attracted enormous attention due to their unique photophysical properties, such as resistance to photobleaching and photoblinking, low background autofluorescence, and long luminescence lifetime. Owing to these unique advantages, UCNPs have been widely examined for biomedical applications, including biosensing, imaging, and theranostics. In this review, we have first summarized the mechanisms for three generally accepted upconversion luminescence processes, i.e., lanthanide (Ln) doped upconversion luminescence, dye-sensitized upconversion, and triplet-triplet annihilation upconversion, and then discussed recent advancements on the preparation, functionalization, and biomedical applications of each type of UCNPs. The review article finally concludes with our perspectives on UCNPs' emerging and potential biomedical applications in the near future.
AB - Upconversion nanoparticles (UCNPs) are one kind of luminescence nanomaterials that convert low energy photons to high energy emissions. These nanomaterials have recently attracted enormous attention due to their unique photophysical properties, such as resistance to photobleaching and photoblinking, low background autofluorescence, and long luminescence lifetime. Owing to these unique advantages, UCNPs have been widely examined for biomedical applications, including biosensing, imaging, and theranostics. In this review, we have first summarized the mechanisms for three generally accepted upconversion luminescence processes, i.e., lanthanide (Ln) doped upconversion luminescence, dye-sensitized upconversion, and triplet-triplet annihilation upconversion, and then discussed recent advancements on the preparation, functionalization, and biomedical applications of each type of UCNPs. The review article finally concludes with our perspectives on UCNPs' emerging and potential biomedical applications in the near future.
UR - http://www.scopus.com/inward/record.url?scp=85040184085&partnerID=8YFLogxK
UR - http://purl.org/au-research/grants/nhmrc/1125794
UR - http://purl.org/au-research/grants/arc/DE170100092
U2 - 10.1039/c7tb02527k
DO - 10.1039/c7tb02527k
M3 - Article
C2 - 32254163
AN - SCOPUS:85040184085
VL - 6
SP - 192
EP - 209
JO - Journal of Materials Chemistry B
JF - Journal of Materials Chemistry B
SN - 2050-7518
IS - 2
ER -