Recombination between the dfrA12-orfF-aadA2 cassette array and an aadA1 gene cassette creates a hybrid cassette, aadA8b

Alicia M. Gestal, H. W. Stokes, Sally R. Partridge, Ruth M. Hall*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Homologous recombination between closely related gene cassettes, such as aadA1 and aadA2, which are 89% identical, can create hybrid cassettes and hybrids of existing cassette arrays. A new cassette array, dfrA12-orfF-aadA8b, which was created by such a recombination event occurring within the aadA2 cassette in the dfrA12-orfF-aadA2 array, has been identified.

Original languageEnglish
Pages (from-to)4771-4774
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number11
DOIs
Publication statusPublished - Nov 2005

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