Abstract
Tumor-infiltrating immune cells play important roles in metastasis. We have recently revealed the recruitment of a specific myeloid cell subset (CD11b/Gr1mid) to hepatic metastases. Such a recruitment relies on CCL2/CCR2 signaling and acts to sustain metastatic growth. A similar cell subset was identified in patients bearing hepatic metastases of colorectal cancer, highlighting the potential therapeutic relevance of our findings.
Original language | English |
---|---|
Article number | e23187 |
Pages (from-to) | 1-2 |
Number of pages | 2 |
Journal | OncoImmunology |
Volume | 2 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 2013 |
Externally published | Yes |