Reduced fetal platelet counts in pregnancies with abnormal Doppler umbilical flow waveforms

Gavin R. Wilcox*, Brian J. Trudinger, Colleen M. Cook, Wendy R. Wilcox, Anita J. Connelly

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Fetal and maternal platelet counts were correlated with antenatal assessment of the umbilical-placental waveform. Forty singleton pregnancies were studied using Doppler ultrasound, and placental resistance was categorized as normal or high according to the systolic/diastolic ratio. We performed platelet counts on maternal and cord blood taken at the time of cesarean section. The high-resistance group had a mean fetal platelet count (218 ± 53 × 103/μL significantly lower than that of the normal-resistance group (314 ± 76 × 103/μL) (P<.001). This difference was evident in both the hypertensive and nonhypertensive subgroups of, the high-resistance group. There was no difference in mean maternal platelet counts between the high- and normal-resistance groups.

Original languageEnglish
Pages (from-to)639-643
Number of pages5
JournalObstetrics and Gynecology
Volume73
Issue number4
Publication statusPublished - 1 Apr 1989
Externally publishedYes

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