TY - JOUR
T1 - Refractive index tomography of turbid media by bifocal optical coherence refractometry
AU - Zvyagin, Andrei V.
AU - Silva, K. K M B Dilusha
AU - Alexandrov, Sergey A.
AU - Hillman, Timothy R.
AU - Armstrong, Julian J.
AU - Tsuzuki, Takuya
AU - Sampson, David D.
PY - 2003
Y1 - 2003
N2 - We demonstrate tomographic imaging of the refractive index of turbid media using bifocal optical coherence refractometry (BOCR). The technique, which is a variant of optical coherence tomography, is based on the measurement of the optical pathlength difference between two foci simultaneously present in a medium of interest. We describe a new method to axially shift the bifocal optical pathlength that avoids the need to physically relocate the objective lens or the sample during an axial scan, and present an experimental realization based on an adaptive liquid-crystal lens. We present experimental results, including video clips, which demonstrate refractive index tomography of a range of turbid liquid phantoms, as well as of human skin in vivo.
AB - We demonstrate tomographic imaging of the refractive index of turbid media using bifocal optical coherence refractometry (BOCR). The technique, which is a variant of optical coherence tomography, is based on the measurement of the optical pathlength difference between two foci simultaneously present in a medium of interest. We describe a new method to axially shift the bifocal optical pathlength that avoids the need to physically relocate the objective lens or the sample during an axial scan, and present an experimental realization based on an adaptive liquid-crystal lens. We present experimental results, including video clips, which demonstrate refractive index tomography of a range of turbid liquid phantoms, as well as of human skin in vivo.
UR - http://www.scopus.com/inward/record.url?scp=2942700000&partnerID=8YFLogxK
U2 - 10.1364/OE.11.003503
DO - 10.1364/OE.11.003503
M3 - Article
C2 - 19471485
AN - SCOPUS:2942700000
SN - 1094-4087
VL - 11
SP - 3503
EP - 3517
JO - Optics Express
JF - Optics Express
IS - 25
ER -