Refractive index tomography of turbid media by bifocal optical coherence refractometry

Andrei V. Zvyagin*, Sergey A. Alexandrov, K. K M B Dilusha Silva, Timothy R. Hillman, Julian J. Armstrong, Takuya Tsuzuki, David D. Sampson

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

1 Citation (Scopus)


We demonstrate tomographic imaging of the refractive index of turbid media using bifocal optical coherence refractometry (BOCR). The technique, which is a variant of optical coherence tomography, is based on the measurement of the optical pathlength difference between two foci simultaneously present in a medium of interest. We describe a new method to axially shift the bifocal optical pathlength that avoids the need to physically relocate the objective lens or the sample during an axial scan, and present an experimental realization based on an adaptive liquid-crystal lens. We present experimental results, including video clips, which demonstrate refractive index tomography of a range of turbid liquid phantoms, as well as of human skin in vivo.

Original languageEnglish
Title of host publicationCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII
Place of PublicationBellingham, Washington
Number of pages12
ISBN (Print)0819452246
Publication statusPublished - 2004
Externally publishedYes

Publication series

NameProceedings of SPIE
ISSN (Print)0277-786X


Dive into the research topics of 'Refractive index tomography of turbid media by bifocal optical coherence refractometry'. Together they form a unique fingerprint.

Cite this