TY - JOUR
T1 - Relationship between angiographic infarct size and left ventricular filling
AU - Cranswick, Richard
AU - Davis, Robyn
AU - Jones, Michael
AU - Hunyor, Stephen N.
PY - 1992
Y1 - 1992
N2 - Infarct size may influence left ventricular filling after acute myocardial infarction. Pulsed Doppler transmitral flow velocities were compared in 47 patients at 7 ± 6 days following acute myocardial infarction and 47 age-matched controls. Patients were stratified by angiographic infarct size into Groups I, II, III (corresponding angiographic hypokinetic scores < 2; 2-2.99; ≥ 3 SD/cord). Early diastolic transmitral Doppler flow velocities did not differ between infarct groups but atrial transmitral Doppler flow measurements did: peak A velocity (p = 0.001), A velocity time integral (p < 0.001), and total velocity time integral (p = 0.001). Compared to controls atrial transmitral Doppler flow was augmented in Group I, whilst atrial and total transmitral Doppler flow were depressed in Group III. Peak A velocity and A velocity time integral were inversely related to infarct size (R = -0.44 to -0.54) and directly to left ventricular ejection fraction (R = 0.59 to 0.65). Large infarct size following myocardial infarction is associated with lower atrial and total transmitral Doppler flow velocities.
AB - Infarct size may influence left ventricular filling after acute myocardial infarction. Pulsed Doppler transmitral flow velocities were compared in 47 patients at 7 ± 6 days following acute myocardial infarction and 47 age-matched controls. Patients were stratified by angiographic infarct size into Groups I, II, III (corresponding angiographic hypokinetic scores < 2; 2-2.99; ≥ 3 SD/cord). Early diastolic transmitral Doppler flow velocities did not differ between infarct groups but atrial transmitral Doppler flow measurements did: peak A velocity (p = 0.001), A velocity time integral (p < 0.001), and total velocity time integral (p = 0.001). Compared to controls atrial transmitral Doppler flow was augmented in Group I, whilst atrial and total transmitral Doppler flow were depressed in Group III. Peak A velocity and A velocity time integral were inversely related to infarct size (R = -0.44 to -0.54) and directly to left ventricular ejection fraction (R = 0.59 to 0.65). Large infarct size following myocardial infarction is associated with lower atrial and total transmitral Doppler flow velocities.
KW - Atrial contribution
KW - Hyperkinesis
KW - Hypokinesis
KW - Left ventricular ejection fraction
UR - http://www.scopus.com/inward/record.url?scp=0026503587&partnerID=8YFLogxK
U2 - 10.1016/0167-5273(92)90183-4
DO - 10.1016/0167-5273(92)90183-4
M3 - Article
C2 - 1572745
AN - SCOPUS:0026503587
SN - 0167-5273
VL - 35
SP - 241
EP - 251
JO - International Journal of Cardiology
JF - International Journal of Cardiology
IS - 2
ER -