Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome: I. Definitions

Manu L. N. G. Malbrain, Michael L. Cheatham, Andrew Kirkpatrick, Michael Sugrue, Michael Parr, Jan De Waele, Zsolt Balogh, Ari Leppäniemi, Claudia Olvera, Rao Ivatury, Scott D'Amours, Julia Wendon, Ken Hillman, Kenth Johansson, Karel Kolkman, Alexander Wilmer

Research output: Contribution to journalArticlepeer-review

1002 Citations (Scopus)


Objective: Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) have been increasingly recognized in the critically ill over the past decade. The variety of definitions proposed has led to confusion and difficulty in comparing one study to another. Design: An international consensus group of critical care specialists convened at the second World Congress on Abdominal Compartment Syndrome to standardize definitions for IAH and ACS based upon the current understanding of the pathophysiology surrounding these two syndromes. Methods: Prior to the conference the authors developed a blueprint for the various definitions, which was further refined both during and after the conference. The present article serves as the final report of the 2004 International ACS Consensus Definitions Conference and is endorsed by the World Society of Abdominal Compartment Syndrome (WSACS). Results: IAH is redefined as an intra-abdominal pressure (IAP) at or above 12 mmHg. ACS is redefined as an IAP above 20 mmHg with evidence of organ dysfunction/failure. ACS is further classified as either primary, secondary, or recurrent based upon the duration and cause of the IAH-induced organ failure. Standards for IAP monitoring are set forth to facilitate accuracy of IAP measurements from patient to patient. Conclusions: State-of-the-art definitions for IAH and ACS are proposed based upon current medical evidence as well as expert opinion. The WSACS recommends that these definitions be used for future clinical and basic science research. Specific guidelines and recommendations for clinical management of patients with IAH/ACS are published in a separate review.

Original languageEnglish
Pages (from-to)1722-1732
Number of pages11
JournalIntensive Care Medicine
Issue number11
Publication statusPublished - 1 Nov 2006
Externally publishedYes


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