Review on gold nanoparticles and their applications

Minakshi Das, Kyu Hwan Shim, Seong Soo A An, Dong Kee Yi

Research output: Contribution to journalReview article

57 Citations (Scopus)

Abstract

Gold nanoparticles are widely used in many fields as preferred materials for their unique optical and physical properties, such as surface plasmon oscillations for labeling, imaging, and sensing. Recently, many advancements were made in biomedical applications with better biocompatibility in disease diagnosis and therapeutics. Au-NPs could be prepared and conjugated with many functionalizing agents, such as polymers, surfactants, ligands, dendrimers, drugs, DNA, RNA, proteins, peptides and oligonucleotides. This review addressed the use of gold nanoparticles and the surface functionalization with a wide range of molecules, expanding and improving gold nanoparticles in targeting drugs for photothermal therapy with reduced cytotoxic effcts in various cancers, gene therapy and many other diseases. Overall, Au-NPs would be a promising vehicle for drug delivery and therapies.

Original languageEnglish
Pages (from-to)193-205
Number of pages13
JournalToxicology and Environmental Health Sciences
Volume3
Issue number4
DOIs
Publication statusPublished - 2011
Externally publishedYes

Keywords

  • Cancer
  • Cytotoxicity
  • Drug delivery
  • Functionalization
  • Gold nanoparticles

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