Rheological properties of the tissues of the central nervous system

A review

Shaokoon Cheng, Elizabeth C. Clarke, Lynne E. Bilston*

*Corresponding author for this work

Research output: Contribution to journalReview article

136 Citations (Scopus)


Knowledge of the biomechanical properties of central nervous system (CNS) tissues is important for understanding mechanisms and thresholds for injury, and aiding development of computer or surrogate models of these tissues. Many investigations have been conducted to estimate the properties of CNS tissues including under shear, compressive and tensile loading, however there is much variability in this body of literature, making it difficult to separate the material properties from effects that result from a given experimental protocol. This review summarises previous studies of brain and spinal cord properties; discussing their main findings and points of difference, and displays the reported data on comparable scales. Additionally, based on the observed effects of methodological choices on reported tissue properties, recommendations for future studies of brain and spinal cord properties are made.

Original languageEnglish
Pages (from-to)1318-1337
Number of pages20
JournalMedical Engineering and Physics
Issue number10
Publication statusPublished - Dec 2008
Externally publishedYes

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