TY - JOUR
T1 - Rheological properties of the tissues of the central nervous system
T2 - A review
AU - Cheng, Shaokoon
AU - Clarke, Elizabeth C.
AU - Bilston, Lynne E.
PY - 2008/12
Y1 - 2008/12
N2 - Knowledge of the biomechanical properties of central nervous system (CNS) tissues is important for understanding mechanisms and thresholds for injury, and aiding development of computer or surrogate models of these tissues. Many investigations have been conducted to estimate the properties of CNS tissues including under shear, compressive and tensile loading, however there is much variability in this body of literature, making it difficult to separate the material properties from effects that result from a given experimental protocol. This review summarises previous studies of brain and spinal cord properties; discussing their main findings and points of difference, and displays the reported data on comparable scales. Additionally, based on the observed effects of methodological choices on reported tissue properties, recommendations for future studies of brain and spinal cord properties are made.
AB - Knowledge of the biomechanical properties of central nervous system (CNS) tissues is important for understanding mechanisms and thresholds for injury, and aiding development of computer or surrogate models of these tissues. Many investigations have been conducted to estimate the properties of CNS tissues including under shear, compressive and tensile loading, however there is much variability in this body of literature, making it difficult to separate the material properties from effects that result from a given experimental protocol. This review summarises previous studies of brain and spinal cord properties; discussing their main findings and points of difference, and displays the reported data on comparable scales. Additionally, based on the observed effects of methodological choices on reported tissue properties, recommendations for future studies of brain and spinal cord properties are made.
UR - http://www.scopus.com/inward/record.url?scp=56249141782&partnerID=8YFLogxK
U2 - 10.1016/j.medengphy.2008.06.003
DO - 10.1016/j.medengphy.2008.06.003
M3 - Review article
C2 - 18614386
AN - SCOPUS:56249141782
SN - 1350-4533
VL - 30
SP - 1318
EP - 1337
JO - Medical Engineering and Physics
JF - Medical Engineering and Physics
IS - 10
ER -