Saccharomyces boulardii - Scope for use in gastrointestinal disorders

A. Sibal, S. M. Davison*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Saccharomyces boulardii (Sb) is a non-pathogenic yeast. Its numerous interesting properties have led to studies of its potential use in gastrointestinal disorders. Different putative mechanisms suggested include toxin neutralisation and polyamine mediated trophic effects on intestine. Sb can be administered orally and has been reported to be remarkably safe. It has been used in acute infectious enteritis, toddler diarrhoea, antibiotic-induced diarrhoea, C. difficile-associated enteropathy, enteral nutrition-associated diarrhoea, chronic diarrhoea in HIV patients, travellers' diarrhoea and Crohn's disease. This article reviews the mechanisms of action of Sb and clinical studies of its use in various gastrointestinal disorders.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalSingapore Paediatric Journal
Issue number4
Publication statusPublished - 1996
Externally publishedYes


  • diarrhoea
  • Saccharomyces boulardii


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