TY - JOUR
T1 - Safety and biocompatibility of a bionic eye
T2 - imaging, intraocular pressure, and histology data
AU - Eggenberger, Samuel C.
AU - James, Natalie L.
AU - Ho, Cherry
AU - Eamegdool, Steven S.
AU - Tatarinoff, Veronika
AU - Craig, Naomi A.
AU - Gow, Barry S.
AU - Wan, Susan
AU - Dodds, Christopher W. D.
AU - La Hood, Donna
AU - Gilmour, Aaron
AU - Donahoe, Shannon L.
AU - Krockenberger, Mark
AU - Tumuluri, Krishna
AU - da Cruz, Melville J.
AU - Grigg, John R.
AU - McCluskey, Peter
AU - Lovell, Nigel H.
AU - Madigan, Michele C.
AU - Fung, Adrian T.
AU - Suaning, Gregg J.
N1 - Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
PY - 2021/12
Y1 - 2021/12
N2 - The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research.
AB - The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research.
KW - Biocompatibility
KW - Histopathology
KW - Intraocular pressure
KW - Opthalmoscopy
KW - Retina
KW - Visual prosthesis
UR - http://www.scopus.com/inward/record.url?scp=85120334159&partnerID=8YFLogxK
UR - http://purl.org/au-research/grants/nhmrc/1109056
UR - http://purl.org/au-research/grants/nhmrc/1087224
U2 - 10.1016/j.dib.2021.107634
DO - 10.1016/j.dib.2021.107634
M3 - Article
C2 - 34988269
AN - SCOPUS:85120334159
SN - 2352-3409
VL - 39
SP - 1
EP - 12
JO - Data in Brief
JF - Data in Brief
M1 - 107634
ER -