Abstract
A disposable device for fractionation of blood into its components that is simple to operate and provides throughput of greater than 1 mL min -1 is highly sought after in medical diagnostics and therapies. This paper describes a device with parallel deterministic lateral displacement devices for enrichment of leukocytes from blood. We show capture of 98% and approximately ten-fold enrichment of leukocytes in whole blood. We demonstrate scaling up through the integration of six parallel devices to achieve a flow rate of 115 νL of undiluted blood per minute per atmosphere of applied pressure.
| Original language | English |
|---|---|
| Article number | 054024 |
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Journal of Micromechanics and Microengineering |
| Volume | 21 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2011 |