Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia

M. A. Qhotsokoane-Lusunzi, P. Karuso

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The medicinal plant Bulbine narcissifolia is used by the Basotho, Griqua, and whites of southern Africa for wound healing and as a mild purgative. Extraction of the powdered root has yielded acetosyringone, chrysophanol, knipholone, isoknipholone, 10,7'-bichrysophanol, and chrysalodin in addition to two new anthraquinone glycosides, knipholone-8-O-β-D-gentiobioside (1) and chrysalodin-10-β-D-gentiobioside (2). NMR spectroscopy was used to elucidate the structures of 1 and 2 and to show that 1 binds weakly to DNA.

LanguageEnglish
Pages1368-1372
Number of pages5
JournalJournal of Natural Products
Volume64
Issue number10
DOIs
Publication statusPublished - 2001

Fingerprint

acetosyringone
laxatives
anthraquinones
Medicinal Plants
Metabolites
tissue repair
Southern Africa
secondary metabolites
medicinal plants
glycosides
nuclear magnetic resonance spectroscopy
Cathartics
Anthraquinones
DNA
Glycosides
Wound Healing
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
knipholone
Xanthorrhoeaceae

Cite this

@article{6eafb8c9bce04adca6e31a526b5fe374,
title = "Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia",
abstract = "The medicinal plant Bulbine narcissifolia is used by the Basotho, Griqua, and whites of southern Africa for wound healing and as a mild purgative. Extraction of the powdered root has yielded acetosyringone, chrysophanol, knipholone, isoknipholone, 10,7'-bichrysophanol, and chrysalodin in addition to two new anthraquinone glycosides, knipholone-8-O-β-D-gentiobioside (1) and chrysalodin-10-β-D-gentiobioside (2). NMR spectroscopy was used to elucidate the structures of 1 and 2 and to show that 1 binds weakly to DNA.",
author = "Qhotsokoane-Lusunzi, {M. A.} and P. Karuso",
year = "2001",
doi = "10.1021/np010279c",
language = "English",
volume = "64",
pages = "1368--1372",
journal = "Journal of Natural Products",
issn = "0163-3864",
publisher = "AMER SOC PHARMACOGNOSY",
number = "10",

}

Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia. / Qhotsokoane-Lusunzi, M. A.; Karuso, P.

In: Journal of Natural Products, Vol. 64, No. 10, 2001, p. 1368-1372.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia

AU - Qhotsokoane-Lusunzi, M. A.

AU - Karuso, P.

PY - 2001

Y1 - 2001

N2 - The medicinal plant Bulbine narcissifolia is used by the Basotho, Griqua, and whites of southern Africa for wound healing and as a mild purgative. Extraction of the powdered root has yielded acetosyringone, chrysophanol, knipholone, isoknipholone, 10,7'-bichrysophanol, and chrysalodin in addition to two new anthraquinone glycosides, knipholone-8-O-β-D-gentiobioside (1) and chrysalodin-10-β-D-gentiobioside (2). NMR spectroscopy was used to elucidate the structures of 1 and 2 and to show that 1 binds weakly to DNA.

AB - The medicinal plant Bulbine narcissifolia is used by the Basotho, Griqua, and whites of southern Africa for wound healing and as a mild purgative. Extraction of the powdered root has yielded acetosyringone, chrysophanol, knipholone, isoknipholone, 10,7'-bichrysophanol, and chrysalodin in addition to two new anthraquinone glycosides, knipholone-8-O-β-D-gentiobioside (1) and chrysalodin-10-β-D-gentiobioside (2). NMR spectroscopy was used to elucidate the structures of 1 and 2 and to show that 1 binds weakly to DNA.

UR - http://www.scopus.com/inward/record.url?scp=0034752437&partnerID=8YFLogxK

U2 - 10.1021/np010279c

DO - 10.1021/np010279c

M3 - Article

VL - 64

SP - 1368

EP - 1372

JO - Journal of Natural Products

T2 - Journal of Natural Products

JF - Journal of Natural Products

SN - 0163-3864

IS - 10

ER -