Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia

M. A. Qhotsokoane-Lusunzi, P. Karuso*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


The medicinal plant Bulbine narcissifolia is used by the Basotho, Griqua, and whites of southern Africa for wound healing and as a mild purgative. Extraction of the powdered root has yielded acetosyringone, chrysophanol, knipholone, isoknipholone, 10,7'-bichrysophanol, and chrysalodin in addition to two new anthraquinone glycosides, knipholone-8-O-β-D-gentiobioside (1) and chrysalodin-10-β-D-gentiobioside (2). NMR spectroscopy was used to elucidate the structures of 1 and 2 and to show that 1 binds weakly to DNA.

Original languageEnglish
Pages (from-to)1368-1372
Number of pages5
JournalJournal of Natural Products
Issue number10
Publication statusPublished - 2001


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