Secretome

Clues into pathogen infection and clinical applications

Shoba Ranganathan*, Gagan Garg

*Corresponding author for this work

Research output: Contribution to journalReview article

34 Citations (Scopus)

Abstract

The secretome encompasses the complete set of gene products secreted by a cell. Recent studies on secretome analysis reveal that secretory proteins play an important role in pathogen infection and host-pathogen interactions. Excretory/secretory proteins of pathogens change the host cell environment by suppressing the immune system, to aid the proliferation of infection. Identifying secretory proteins involved in pathogen infection will lead to the discovery of potential drug targets and biomarkers for diagnostic applications.

Original languageEnglish
Article number113
Pages (from-to)1-7
Number of pages7
JournalGenome Medicine
Volume1
Issue number11
DOIs
Publication statusPublished - 30 Nov 2009

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