Seeing the difference: painless progressive vision loss in a vasculopath

Jenny L. Hepschke*, Katherine Masselos, Jennifer Sandbach, Clare L. Fraser

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


A 78-year-old Caucasian man with significant vascular disease reported sudden onset of worsened vision during a routine wound-care appointment for nonhealing necrotic leg ulcers. He described painless blurring of vision with grey scotomas in his right eye, his only well-seeing eye, after trauma to the left eye as a child. He presented with retinal ischemia, a cotton wool spot, and optic nerve swelling. Temporal artery biopsy showed myxoid degeneration and extensive calcium deposition, which also was present on imaging throughout his carotid and vertebral arterial system—the clinical picture of calciphylaxis.

Original languageEnglish
Pages (from-to)123-131
Number of pages9
JournalSurvey of Ophthalmology
Issue number1
Publication statusPublished - 1 Jan 2019
Externally publishedYes


  • calciphylaxis
  • ischemic optic neuropathy
  • painless vision loss
  • retinal ischemia


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