Segmented magnetic nanofibers for single cell manipulation

Jun Liu, Jian Shi, Lianmei Jiang, Fan Zhang, Li Wang, Shinpei Yamamoto, Mikio Takano, Mengjie Chang, Haoli Zhang, Yong Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


We report a simple but straightforward approach to fabricate magnetic nanofiber segments for cell manipulation. Electrospinning was used to produce nanofibers from a magnetic nanoparticles containing polymethylglutarimide (PMGI) precursor solution. After sonication, the fabricated nanofibers were uniformly segmented. When dispersed in an aqueous solution, the orientation of the fiber segments could easily be controlled by an external magnetic field. NIH 3T3 cells were then cultured in a medium containing magnetic fibers, resulting in stable cell-nanofiber hybrids which can be conveniently manipulated with a magnet.

Original languageEnglish
Pages (from-to)7530-7535
Number of pages6
JournalApplied Surface Science
Issue number19
Publication statusPublished - 15 Jul 2012
Externally publishedYes


  • Cell culture
  • Magnetic manipulation
  • Nanofibers


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