TY - JOUR
T1 - Self-assembly mechanism of folate-templated mesoporous silica
AU - Atluri, Rambabu
AU - Iqbal, Muhammad Naeem
AU - Bacsik, Zoltan
AU - Hedin, Niklas
AU - Villaescusa, Luis Angel
AU - Garcia-Bennett, Alfonso E.
PY - 2013/9/24
Y1 - 2013/9/24
N2 - A method to form ordered mesoporous silica based on the use of folate supramolecular templates has been developed. Evidence based on in situ small-angle X-ray scattering (SAXS), electron microscopy, infrared spectroscopy, and in situ conductivity measurements are used to investigate the organic-inorganic interactions and synthesis mechanism. The behavior of folate molecules in solution differs distinctively from that of surfactants commonly used for the preparation of ordered mesoporous silica phases, notably with the absence of a critical micellar concentration. In situ SAXS studies reveal fluctuations in X-ray scattering intensities consistent with the condensation of the silica precursor surrounding the folate template and the growth of the silica mesostructure in the initial stages. High-angle X-ray diffraction shows that the folate template is well-ordered within the pores even after a few minutes of synthesis. Direct structural data for the self-assembly of folates into chiral tetramers within the pores of mesoporous silica provide evidence for the in register stacking of folate tetramers, resulting in a chiral surface of rotated tetramers, with a rotation angle of 30. Additionally, the self-assembled folates within pores were capable of adsorbing a considerable amount of CO 2 gas through the cavity space of the tetramers. The study demonstrates the validity of using a naturally occurring template to produce relevant and functional mesoporous materials.
AB - A method to form ordered mesoporous silica based on the use of folate supramolecular templates has been developed. Evidence based on in situ small-angle X-ray scattering (SAXS), electron microscopy, infrared spectroscopy, and in situ conductivity measurements are used to investigate the organic-inorganic interactions and synthesis mechanism. The behavior of folate molecules in solution differs distinctively from that of surfactants commonly used for the preparation of ordered mesoporous silica phases, notably with the absence of a critical micellar concentration. In situ SAXS studies reveal fluctuations in X-ray scattering intensities consistent with the condensation of the silica precursor surrounding the folate template and the growth of the silica mesostructure in the initial stages. High-angle X-ray diffraction shows that the folate template is well-ordered within the pores even after a few minutes of synthesis. Direct structural data for the self-assembly of folates into chiral tetramers within the pores of mesoporous silica provide evidence for the in register stacking of folate tetramers, resulting in a chiral surface of rotated tetramers, with a rotation angle of 30. Additionally, the self-assembled folates within pores were capable of adsorbing a considerable amount of CO 2 gas through the cavity space of the tetramers. The study demonstrates the validity of using a naturally occurring template to produce relevant and functional mesoporous materials.
UR - http://www.scopus.com/inward/record.url?scp=84884836115&partnerID=8YFLogxK
U2 - 10.1021/la401532j
DO - 10.1021/la401532j
M3 - Article
C2 - 23971901
AN - SCOPUS:84884836115
SN - 0743-7463
VL - 29
SP - 12003
EP - 12012
JO - Langmuir
JF - Langmuir
IS - 38
ER -