Abstract
Rare-earth doped upconversion nanocrystals are emerging as the next-generation luminescent biomaterials. Here we load NaYF4: Yb/Er and NaYF4: Yb/Tm upconversion nanocrystals into a soft-glass suspended-core optical fiber dip sensor, allowing sensitive measurements and power-dependent characterizations to be performed. This, in combination with negligible background autofluorescence from the glass fiber when using infrared excitation has provided a significant improvement in terms of sensitivity over what has previously been demonstrated using an optical fiber dip sensor. For detection we employ suspended-core optical fibers, which have found extensive use in sensing applications. These combine the high evanescent overlap comparable to that of a nanowire, with the robust handling characteristics and long interaction length of a conventional fiber. The fiber sensor platform allows measurements to be performed using minimal sample volumes (<20 nL) while still maintaining the sensitivity of the platform.
Original language | English |
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Title of host publication | Colloidal Nanocrystals for Biomedical Applications VIII |
Place of Publication | Bellingham, Washington |
Publisher | SPIE |
Pages | 1-6 |
Number of pages | 6 |
Volume | 8595 |
ISBN (Print) | 9780819493644 |
DOIs | |
Publication status | Published - 2013 |
Event | Colloidal Nanocrystals for Biomedical Applications VIII - San Francisco, CA, United States Duration: 2 Feb 2013 → 4 Feb 2013 |
Other
Other | Colloidal Nanocrystals for Biomedical Applications VIII |
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Country/Territory | United States |
City | San Francisco, CA |
Period | 2/02/13 → 4/02/13 |