Abstract
A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.
Original language | English |
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Pages (from-to) | 613-615 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 46 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2010 |
Externally published | Yes |