SERS aptasensor from nanorod-nanoparticle junction for protein detection

Yuling Wang, Kyuwan Lee, Joseph Irudayaraj*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

98 Citations (Scopus)


A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.

Original languageEnglish
Pages (from-to)613-615
Number of pages3
JournalChemical Communications
Issue number4
Publication statusPublished - 2010
Externally publishedYes


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