Severe Guillain-Barré syndrome following head trauma

Ik Lin Tan; Thomas Ng; Steve Vucic

doi:10.1016/j.jocn.2009.11.037

Severe Guillain-Barré syndrome following head trauma

Ik Lin Tan, Thomas Ng, Steve Vucic^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Fulminant forms of Guillain-Barré syndrome (GBS) present as acute onset tetraparesis and areflexia with absent brainstem reflexes, simulating brain death. Head trauma as an antecedent to fulminant GBS has been infrequently reported, and recognizing an association between GBS and head trauma may be crucial for patient management. Consequently, we report a patient with fulminant GBS with mixed demyelinating and axonal features preceded by a closed head injury, and discuss the possible pathophysiological mechanisms.

Original language	English
Pages (from-to)	1452-1454
Number of pages	3
Journal	Journal of Clinical Neuroscience
Volume	17
Issue number	11
DOIs	https://doi.org/10.1016/j.jocn.2009.11.037
Publication status	Published - Nov 2010
Externally published	Yes

Keywords

AMSAN
Guillain-Barré syndrome
Head trauma

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10.1016/j.jocn.2009.11.037

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abstract = "Fulminant forms of Guillain-Barr{\'e} syndrome (GBS) present as acute onset tetraparesis and areflexia with absent brainstem reflexes, simulating brain death. Head trauma as an antecedent to fulminant GBS has been infrequently reported, and recognizing an association between GBS and head trauma may be crucial for patient management. Consequently, we report a patient with fulminant GBS with mixed demyelinating and axonal features preceded by a closed head injury, and discuss the possible pathophysiological mechanisms.",

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AU - Ng, Thomas

AU - Vucic, Steve

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AB - Fulminant forms of Guillain-Barré syndrome (GBS) present as acute onset tetraparesis and areflexia with absent brainstem reflexes, simulating brain death. Head trauma as an antecedent to fulminant GBS has been infrequently reported, and recognizing an association between GBS and head trauma may be crucial for patient management. Consequently, we report a patient with fulminant GBS with mixed demyelinating and axonal features preceded by a closed head injury, and discuss the possible pathophysiological mechanisms.

KW - AMSAN

KW - Guillain-Barré syndrome

KW - Head trauma

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ER -

Severe Guillain-Barré syndrome following head trauma

Abstract

Keywords

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