Silver nanostructure sensing platform for maximum-contrast fluorescence cell imaging

Kyung-Min Lee, Arup Neogi, Purnima Basu Neogi, Minjung Kim, Bongsoo Kim, Rafal Luchowski, Zygmunt Gryczynski, Nils Calander, Tae-Youl Choi

Research output: Contribution to journalArticle

4 Citations (Scopus)
4 Downloads (Pure)

Abstract

We present herein a silver nanostructure-assisted sensing platform which consists of a combined structure of Ag nanowire (NW) and nanodot (ND) array. Highly enhanced fluorescence from fluorophore is attributed to a strongly coupled optical near-field interaction between proximately located Ag NW and NDs. We obtained enhanced fluorescence intensity with up to 140 folds, as contrasted from background intensity, reaching a theoretical maximum value. On the other hand, fluorescence lifetime was greatly reduced to 0.27 ns (from 2.17 ns for the same fluorophores without nanostructure). This novel platform can be a promising utility for optical imaging and labeling of biological systems with a great sensitivity.
Original languageEnglish
Pages (from-to)056008-1-056008-5
Number of pages5
JournalJournal of Biomedical Optics
Volume16
Issue number5
DOIs
Publication statusPublished - 2011

Bibliographical note

Copyright 2011 Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

  • Ag nanowire
  • Cell imaging
  • Fluorescence
  • Focused ion beam
  • Nanodot

Fingerprint Dive into the research topics of 'Silver nanostructure sensing platform for maximum-contrast fluorescence cell imaging'. Together they form a unique fingerprint.

  • Cite this

    Lee, K-M., Neogi, A., Neogi, P. B., Kim, M., Kim, B., Luchowski, R., ... Choi, T-Y. (2011). Silver nanostructure sensing platform for maximum-contrast fluorescence cell imaging. Journal of Biomedical Optics, 16(5), 056008-1-056008-5. https://doi.org/10.1117/1.3579157