Simultaneous concentration and separation of proteins in a nanochannel

David W. Inglis; Ewa M. Goldys; Nils P. Calander

doi:10.1002/anie.201100236

Simultaneous concentration and separation of proteins in a nanochannel

David W. Inglis^*, Ewa M. Goldys, Nils P. Calander

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

Balancing the forces: Conductivity gradient focusing in a nanochannel achieves simultaneous separation and concentration of proteins without a temperature gradient, membrane, matrix, ampholytes, or external pump. The electrophoretic force (see picture; red arrow) that dominates at the low-salt side (-) balances the electro-osmotic force (blue) at the high-salt side (+).

Original language	English
Pages (from-to)	7546-7550
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	33
DOIs	https://doi.org/10.1002/anie.201100236
Publication status	Published - 8 Aug 2011

Access to Document

10.1002/anie.201100236

Cite this

@article{0240310949254b5c97929c5f2a7ec19c,

title = "Simultaneous concentration and separation of proteins in a nanochannel",

abstract = "Balancing the forces: Conductivity gradient focusing in a nanochannel achieves simultaneous separation and concentration of proteins without a temperature gradient, membrane, matrix, ampholytes, or external pump. The electrophoretic force (see picture; red arrow) that dominates at the low-salt side (-) balances the electro-osmotic force (blue) at the high-salt side (+).",

author = "Inglis, {David W.} and Goldys, {Ewa M.} and Calander, {Nils P.}",

year = "2011",

month = aug,

day = "8",

doi = "10.1002/anie.201100236",

language = "English",

volume = "50",

pages = "7546--7550",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "Wiley-VCH, Wiley",

number = "33",

}

TY - JOUR

T1 - Simultaneous concentration and separation of proteins in a nanochannel

AU - Inglis, David W.

AU - Goldys, Ewa M.

AU - Calander, Nils P.

PY - 2011/8/8

Y1 - 2011/8/8

N2 - Balancing the forces: Conductivity gradient focusing in a nanochannel achieves simultaneous separation and concentration of proteins without a temperature gradient, membrane, matrix, ampholytes, or external pump. The electrophoretic force (see picture; red arrow) that dominates at the low-salt side (-) balances the electro-osmotic force (blue) at the high-salt side (+).

AB - Balancing the forces: Conductivity gradient focusing in a nanochannel achieves simultaneous separation and concentration of proteins without a temperature gradient, membrane, matrix, ampholytes, or external pump. The electrophoretic force (see picture; red arrow) that dominates at the low-salt side (-) balances the electro-osmotic force (blue) at the high-salt side (+).

UR - http://www.scopus.com/inward/record.url?scp=79961218748&partnerID=8YFLogxK

U2 - 10.1002/anie.201100236

DO - 10.1002/anie.201100236

M3 - Article

C2 - 21710667

AN - SCOPUS:79961218748

SN - 1433-7851

VL - 50

SP - 7546

EP - 7550

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 33

ER -

Simultaneous concentration and separation of proteins in a nanochannel

Abstract

Access to Document

Other files and links

Fingerprint

Cite this