Size-based separation of E. Coli using viscoelastic microfluidics

Tianlong Zhang; Ling Liu; David W. Inglis; Yoichiroh Hosokawa; Yaxiaer Yalikun; Ming Li

Size-based separation of E. Coli using viscoelastic microfluidics

Tianlong Zhang, Ling Liu, David W. Inglis, Yoichiroh Hosokawa, Yaxiaer Yalikun^*, Ming Li^*

^*Corresponding author for this work

School of Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

Abstract

Here, we achieve the separation of Escherichia coli (E. coli) clusters from its singlets using a viscoelastic microfluidic device. In this work, 1- and 4.8-μm polystyrene particles are used to mimic E. coli singlets and clusters. Results show that 4.8- and 1-μm particles are arranged close to the channel centerline and sidewalls, respectively. Also, separation of E. coli singlets and clusters is demonstrated. Considering the significant role of E. coli clusters in biology and the importance of biofilms in nature, this microfluidic platform hopes to be extended for various applications across a range of scientific fields.

Original language	English
Title of host publication	The 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) proceedings
Place of Publication	Piscataway, NJ
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Pages	1998-2001
Number of pages	4
ISBN (Electronic)	9784886864352
ISBN (Print)	9798350333022
Publication status	Published - 2023
Event	22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023 - Kyoto, Japan Duration: 25 Jun 2023 → 29 Jun 2023

Publication series

Name
ISSN (Print)	2167-0013
ISSN (Electronic)	2167-0021

Conference

Conference	22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
Country/Territory	Japan
City	Kyoto
Period	25/06/23 → 29/06/23

Keywords

E. coli
viscoelastic microfluidics
cell separation
bacterial biofilms

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https://ieeexplore.ieee.org/document/10516838

Cite this

Zhang, T., Liu, L., Inglis, D. W., Hosokawa, Y., Yalikun, Y., & Li, M. (2023). Size-based separation of E. Coli using viscoelastic microfluidics. In The 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) proceedings (pp. 1998-2001). Institute of Electrical and Electronics Engineers (IEEE). https://ieeexplore.ieee.org/document/10516838

@inproceedings{19fdcd1d6e6e45f6b1d0f1b9aa01a8a9,

title = "Size-based separation of E. Coli using viscoelastic microfluidics",

abstract = "Here, we achieve the separation of Escherichia coli (E. coli) clusters from its singlets using a viscoelastic microfluidic device. In this work, 1- and 4.8-μm polystyrene particles are used to mimic E. coli singlets and clusters. Results show that 4.8- and 1-μm particles are arranged close to the channel centerline and sidewalls, respectively. Also, separation of E. coli singlets and clusters is demonstrated. Considering the significant role of E. coli clusters in biology and the importance of biofilms in nature, this microfluidic platform hopes to be extended for various applications across a range of scientific fields.",

keywords = "E. coli, viscoelastic microfluidics, cell separation, bacterial biofilms",

author = "Tianlong Zhang and Ling Liu and Inglis, {David W.} and Yoichiroh Hosokawa and Yaxiaer Yalikun and Ming Li",

year = "2023",

language = "English",

isbn = "9798350333022",

publisher = "Institute of Electrical and Electronics Engineers (IEEE)",

pages = "1998--2001",

booktitle = "The 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) proceedings",

address = "United States",

note = "22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023 ; Conference date: 25-06-2023 Through 29-06-2023",

}

Zhang, T, Liu, L , Inglis, DW, Hosokawa, Y, Yalikun, Y & Li, M 2023, Size-based separation of E. Coli using viscoelastic microfluidics. in The 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) proceedings. Institute of Electrical and Electronics Engineers (IEEE), Piscataway, NJ, pp. 1998-2001, 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023, Kyoto, Japan, 25/06/23. <https://ieeexplore.ieee.org/document/10516838>

Size-based separation of E. Coli using viscoelastic microfluidics. / Zhang, Tianlong; Liu, Ling ; Inglis, David W. et al.
The 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) proceedings. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE), 2023. p. 1998-2001.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

TY - GEN

T1 - Size-based separation of E. Coli using viscoelastic microfluidics

AU - Zhang, Tianlong

AU - Liu, Ling

AU - Inglis, David W.

AU - Hosokawa, Yoichiroh

AU - Yalikun, Yaxiaer

AU - Li, Ming

PY - 2023

Y1 - 2023

N2 - Here, we achieve the separation of Escherichia coli (E. coli) clusters from its singlets using a viscoelastic microfluidic device. In this work, 1- and 4.8-μm polystyrene particles are used to mimic E. coli singlets and clusters. Results show that 4.8- and 1-μm particles are arranged close to the channel centerline and sidewalls, respectively. Also, separation of E. coli singlets and clusters is demonstrated. Considering the significant role of E. coli clusters in biology and the importance of biofilms in nature, this microfluidic platform hopes to be extended for various applications across a range of scientific fields.

AB - Here, we achieve the separation of Escherichia coli (E. coli) clusters from its singlets using a viscoelastic microfluidic device. In this work, 1- and 4.8-μm polystyrene particles are used to mimic E. coli singlets and clusters. Results show that 4.8- and 1-μm particles are arranged close to the channel centerline and sidewalls, respectively. Also, separation of E. coli singlets and clusters is demonstrated. Considering the significant role of E. coli clusters in biology and the importance of biofilms in nature, this microfluidic platform hopes to be extended for various applications across a range of scientific fields.

KW - E. coli

KW - viscoelastic microfluidics

KW - cell separation

KW - bacterial biofilms

UR - http://www.scopus.com/inward/record.url?scp=85193541734&partnerID=8YFLogxK

M3 - Conference proceeding contribution

AN - SCOPUS:85193541734

SN - 9798350333022

SP - 1998

EP - 2001

BT - The 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) proceedings

PB - Institute of Electrical and Electronics Engineers (IEEE)

CY - Piscataway, NJ

T2 - 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023

Y2 - 25 June 2023 through 29 June 2023

ER -

Size-based separation of E. Coli using viscoelastic microfluidics

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