Sleep disorders and respiratory function in amyotrophic lateral sclerosis

Rebekah M. Ahmed*, Rowena E. A. Newcombe, Amanda J. Piper, Simon J. Lewis, Brendon J. Yee, Matthew C. Kiernan, Ron R. Grunstein

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)


Sleep disorders in amyotrophic lateral sclerosis (ALS) present a significant challenge to the management of patients. Issues include the maintenance of adequate ventilatory status through techniques such as non-invasive ventilation, which has the ability to modulate survival and improve patient quality of life. Here, a multidisciplinary approach to the management of these disorders is reviewed, from concepts about the underlying neurobiological basis, through to current management approaches and future directions for research.

Original languageEnglish
Pages (from-to)33-42
Number of pages10
JournalSleep Medicine Reviews
Publication statusPublished - Apr 2016
Externally publishedYes


  • Amyotrophic lateral sclerosis
  • Respiratory
  • Sleep
  • Ventilation


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