Sleep-Wake cycle and melatonin rhythms in adolescents and young adults with mood disorders

Comparison of unipolar and bipolar phenotypes

R. Robillard, S. L. Naismith, N. L. Rogers, E. M. Scott, T. K C Ip, D. F. Hermens, I. B. Hickie*

*Corresponding author for this work

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

This study evaluated the potential of circadian measures as early markers of mood disorders subtypes. Patients with bipolar disorders had significantly lower levels and later onset of melatonin secretion than those with unipolar depression. Furthermore, abnormal phase angles between sleep, melatonin and temperature were found in several patients.

Original languageEnglish
Pages (from-to)412-416
Number of pages5
JournalEuropean Psychiatry
Volume28
Issue number7
DOIs
Publication statusPublished - Sep 2013
Externally publishedYes

Keywords

  • Actigraphy
  • Bipolar disorder
  • Circadian
  • Core body temperature
  • Depression
  • Melatonin

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