Spatial reorganization of F-actin in respiratory cells as measured by Brillouin microscopy

H. Mahmodi, P. Bradbury, A. Cidem, H. X. Ong, D. Traini, I. Kabakova*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

Brillouin microscopy has emerged as a non-invasive and label-free technique to map micro-mechanical properties of cells. Here we apply Brillouin microscopy to probe reorganization of F-actin network in respiratory cells treated with Timothy grass pollen protein extracts. The results of our measurements in conjunction with clustering data analysis confirm spatial cellular reorganization of F-actin proteins and compromised junctional integrity in treated cells as compared to controls.

Original languageEnglish
Title of host publicationEmerging Technologies for Cell and Tissue Characterization II
EditorsSeemantini K. Nadkarni, Giuliano Scarcelli
Place of PublicationWashinton
PublisherSPIE
Pages1-2
Number of pages2
ISBN (Electronic)9781510664685
ISBN (Print)9781510664678
DOIs
Publication statusPublished - 2023
EventEmerging Technologies for Cell and Tissue Characterization II 2023 - Munich, Germany
Duration: 28 Jun 202329 Jun 2023

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume12629
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceEmerging Technologies for Cell and Tissue Characterization II 2023
Country/TerritoryGermany
CityMunich
Period28/06/2329/06/23

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