Spontaneous conceptions within two years of having a first infant with assisted conception

Karen Wynter*, Catherine McMahon, Karin Hammarberg, John McBain, Jacky Boivin, Frances Gibson, Jane Fisher

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background Australian data regarding spontaneous conceptions following a live birth conceived by assisted reproductive technologies (ART) have not yet been reported. Aims This study aimed to determine the incidence of spontaneous conceptions within 18-24 months after women had a first infant conceived by ART (ARTC) or spontaneously conceived (SC). Factors associated with spontaneous pregnancies in women with ARTC first infants were investigated. Materials and Methods Nulliparous women were recruited through ART clinics (n = 297) and maternity hospitals (n = 295) in Melbourne and Sydney, Australia. Participants were interviewed in pregnancy and when their first infants were aged 18-24 months. Information was collected on pregnancies since the first infant's birth. The outcome was any subsequent conception during this period. Results Follow-up data were available for 198 women with SC first infants and 236 women with ARTC first infants, 94 (40%) of whom had further ART following the first birth. Spontaneous conceptions had occurred in 40% of women with SC first infants and 33% of women with ARTC first infants who had not had subsequent ART. Twenty-four per cent of pregnancies after the birth of SC first infants were unexpected, compared with 61% of subsequent pregnancies (without further treatment) after the birth of ARTC first infants (P < 0.001). Subsequent, spontaneous pregnancies in women with ARTC first infants were significantly associated with unexplained infertility and shorter partner relationship duration. Discussion Discussion about contraception is recommended if women with ARTC first infants do not wish to have more children or wish to delay subsequent pregnancies.

Original languageEnglish
Pages (from-to)471-476
Number of pages6
JournalAustralian and New Zealand Journal of Obstetrics and Gynaecology
Volume53
Issue number5
DOIs
Publication statusPublished - Oct 2013

Fingerprint Dive into the research topics of 'Spontaneous conceptions within two years of having a first infant with assisted conception'. Together they form a unique fingerprint.

Cite this