Standard guidelines for the chromosome-centric human proteome project

Young Ki Paik, Gilbert S. Omenn, Mathias Uhlen, Samir Hanash, György Marko-Varga, Ruedi Aebersold, Amos Bairoch, Tadashi Yamamoto, Pierre Legrain, Hyoung Joo Lee, Keun Na, Seul Ki Jeong, Fuchu He, Pierre Alain Binz, Toshihide Nishimura, Paul Keown, Mark S. Baker, Jong Shin Yoo, Jerome Garin, Alexander Archakov & 3 others John Bergeron, Ghasem Hosseini Salekdeh, William S. Hancock

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-HPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing colocated genes and their protein products. The C-HPP aims to foster the development of proteome analysis and integration of the findings from related molecular -omics technology platforms through collaborations among universities, industries, and private research groups. The C-HPP consortium leadership has elicited broad input for standard guidelines to manage these international efforts more efficiently by mobilizing existing resources and collaborative networks. The C-HPP guidelines set out the collaborative consensus of the C-HPP teams, introduce topics associated with experimental approaches, data production, quality control, treatment, and transparency of data, governance of the consortium, and collaborative benefits. A companion approach for the Biology and Disease-Driven HPP (B/D-HPP) component of the Human Proteome Project is currently being organized, building upon the Human Proteome Organization's organ-based and biofluid-based initiatives (www.hupo.org/research). The common application of these guidelines in the participating laboratories is expected to facilitate the goal of a comprehensive analysis of the human proteome.

LanguageEnglish
Pages2005-2013
Number of pages9
JournalJournal of Proteome Research
Volume11
Issue number4
DOIs
Publication statusPublished - 6 Apr 2012

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Human Chromosomes
Proteome
Chromosomes
Guidelines
Proteins
Chromosome Mapping
Research
Quality Control
Transparency
Quality control
Consensus
Industry
Genes
Technology

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Paik, Y. K., Omenn, G. S., Uhlen, M., Hanash, S., Marko-Varga, G., Aebersold, R., ... Hancock, W. S. (2012). Standard guidelines for the chromosome-centric human proteome project. Journal of Proteome Research, 11(4), 2005-2013. https://doi.org/10.1021/pr200824a
Paik, Young Ki ; Omenn, Gilbert S. ; Uhlen, Mathias ; Hanash, Samir ; Marko-Varga, György ; Aebersold, Ruedi ; Bairoch, Amos ; Yamamoto, Tadashi ; Legrain, Pierre ; Lee, Hyoung Joo ; Na, Keun ; Jeong, Seul Ki ; He, Fuchu ; Binz, Pierre Alain ; Nishimura, Toshihide ; Keown, Paul ; Baker, Mark S. ; Yoo, Jong Shin ; Garin, Jerome ; Archakov, Alexander ; Bergeron, John ; Salekdeh, Ghasem Hosseini ; Hancock, William S. / Standard guidelines for the chromosome-centric human proteome project. In: Journal of Proteome Research. 2012 ; Vol. 11, No. 4. pp. 2005-2013.
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Paik, YK, Omenn, GS, Uhlen, M, Hanash, S, Marko-Varga, G, Aebersold, R, Bairoch, A, Yamamoto, T, Legrain, P, Lee, HJ, Na, K, Jeong, SK, He, F, Binz, PA, Nishimura, T, Keown, P, Baker, MS, Yoo, JS, Garin, J, Archakov, A, Bergeron, J, Salekdeh, GH & Hancock, WS 2012, 'Standard guidelines for the chromosome-centric human proteome project', Journal of Proteome Research, vol. 11, no. 4, pp. 2005-2013. https://doi.org/10.1021/pr200824a

Standard guidelines for the chromosome-centric human proteome project. / Paik, Young Ki; Omenn, Gilbert S.; Uhlen, Mathias; Hanash, Samir; Marko-Varga, György; Aebersold, Ruedi; Bairoch, Amos; Yamamoto, Tadashi; Legrain, Pierre; Lee, Hyoung Joo; Na, Keun; Jeong, Seul Ki; He, Fuchu; Binz, Pierre Alain; Nishimura, Toshihide; Keown, Paul; Baker, Mark S.; Yoo, Jong Shin; Garin, Jerome; Archakov, Alexander; Bergeron, John; Salekdeh, Ghasem Hosseini; Hancock, William S.

In: Journal of Proteome Research, Vol. 11, No. 4, 06.04.2012, p. 2005-2013.

Research output: Contribution to journalReview articleResearchpeer-review

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AU - Hanash, Samir

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AU - Aebersold, Ruedi

AU - Bairoch, Amos

AU - Yamamoto, Tadashi

AU - Legrain, Pierre

AU - Lee, Hyoung Joo

AU - Na, Keun

AU - Jeong, Seul Ki

AU - He, Fuchu

AU - Binz, Pierre Alain

AU - Nishimura, Toshihide

AU - Keown, Paul

AU - Baker, Mark S.

AU - Yoo, Jong Shin

AU - Garin, Jerome

AU - Archakov, Alexander

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AU - Salekdeh, Ghasem Hosseini

AU - Hancock, William S.

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Paik YK, Omenn GS, Uhlen M, Hanash S, Marko-Varga G, Aebersold R et al. Standard guidelines for the chromosome-centric human proteome project. Journal of Proteome Research. 2012 Apr 6;11(4):2005-2013. https://doi.org/10.1021/pr200824a