Starch-borate-graphene oxide nanocomposites as highly efficient targeted antitumor drugs

Rumei Cheng; Shengju Ou; Yexu Bu; Xuan Li; Xiaohong Liu; Yuqin Wang; Rui Guo; Bingyang Shi; Dayong Jin; Yong Liu

doi:10.1039/c5ra17622k

Starch-borate-graphene oxide nanocomposites as highly efficient targeted antitumor drugs

Rumei Cheng, Shengju Ou, Yexu Bu, Xuan Li, Xiaohong Liu, Yuqin Wang, Rui Guo, Bingyang Shi, Dayong Jin^*, Yong Liu

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We synthesized novel borate antitumor drugs sourced from starch-borate-graphene oxide (SBG) nanocomposites. In vitro results suggest that SBG from the molar ratio of n_starch:n_borate:n_GO at 2:1:1 exhibits excellent biocompatibility with normal human cells (>90% cell viability), but are highly toxic against cancer cells (<20% cell viability).

Original language	English
Pages (from-to)	94855-94858
Number of pages	4
Journal	RSC Advances
Volume	5
Issue number	115
DOIs	https://doi.org/10.1039/c5ra17622k
Publication status	Published - 2015

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title = "Starch-borate-graphene oxide nanocomposites as highly efficient targeted antitumor drugs",

abstract = "We synthesized novel borate antitumor drugs sourced from starch-borate-graphene oxide (SBG) nanocomposites. In vitro results suggest that SBG from the molar ratio of nstarch:nborate:nGO at 2:1:1 exhibits excellent biocompatibility with normal human cells (>90% cell viability), but are highly toxic against cancer cells (<20% cell viability).",

author = "Rumei Cheng and Shengju Ou and Yexu Bu and Xuan Li and Xiaohong Liu and Yuqin Wang and Rui Guo and Bingyang Shi and Dayong Jin and Yong Liu",

year = "2015",

doi = "10.1039/c5ra17622k",

language = "English",

volume = "5",

pages = "94855--94858",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Starch-borate-graphene oxide nanocomposites as highly efficient targeted antitumor drugs

AU - Cheng, Rumei

AU - Ou, Shengju

AU - Bu, Yexu

AU - Li, Xuan

AU - Liu, Xiaohong

AU - Wang, Yuqin

AU - Guo, Rui

AU - Shi, Bingyang

AU - Jin, Dayong

AU - Liu, Yong

PY - 2015

Y1 - 2015

N2 - We synthesized novel borate antitumor drugs sourced from starch-borate-graphene oxide (SBG) nanocomposites. In vitro results suggest that SBG from the molar ratio of nstarch:nborate:nGO at 2:1:1 exhibits excellent biocompatibility with normal human cells (>90% cell viability), but are highly toxic against cancer cells (<20% cell viability).

AB - We synthesized novel borate antitumor drugs sourced from starch-borate-graphene oxide (SBG) nanocomposites. In vitro results suggest that SBG from the molar ratio of nstarch:nborate:nGO at 2:1:1 exhibits excellent biocompatibility with normal human cells (>90% cell viability), but are highly toxic against cancer cells (<20% cell viability).

UR - http://www.scopus.com/inward/record.url?scp=84946925056&partnerID=8YFLogxK

U2 - 10.1039/c5ra17622k

DO - 10.1039/c5ra17622k

M3 - Article

AN - SCOPUS:84946925056

SN - 2046-2069

VL - 5

SP - 94855

EP - 94858

JO - RSC Advances

JF - RSC Advances

IS - 115

ER -

Starch-borate-graphene oxide nanocomposites as highly efficient targeted antitumor drugs

Abstract

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