Abstract
Statins are effective and well-tolerated hypolipidaemic agents which have been increasingly studied for their pleiotropic immunomodulatory and anti-inflammatory effects. Statins have potential therapeutic benefit in a range of neuro-ophthalmological conditions but may also induce or exacerbate certain neurological disorders. This literature review examines evidence from clinical and in vitro studies assessing the effects of statins in myasthenia gravis, myopathy, multiple sclerosis, neuromyelitis optica, idiopathic intracranial hypertension (pseudotumour cerebri), migraine, giant cell arteritis, Bell’s palsy, ocular ischaemia, stroke, Alzheimer’s disease and Parkinson’s disease.
| Original language | English |
|---|---|
| Pages (from-to) | 219-237 |
| Number of pages | 19 |
| Journal | Neuro-Ophthalmology |
| Volume | 45 |
| Issue number | 4 |
| Early online date | 24 Jun 2020 |
| DOIs | |
| Publication status | Published - 4 Jul 2021 |
| Externally published | Yes |
Keywords
- migraine
- multiple sclerosis
- Myasthenia gravis
- myopathy
- optic neuritis
- stroke