TY - JOUR
T1 - Subjective well-being, but not subjective mental functioning shows positive associations with neuropsychological performance in schizophrenia-spectrum disorders
AU - Schroeder, Katrin
AU - Huber, Christian G.
AU - Jelinek, Lena
AU - Moritz, Steffen
PY - 2013/10
Y1 - 2013/10
N2 - Objective To assess the association of subjective quality of life as measured by the Subjective Well-being under Neuroleptic Treatment questionnaire (SWN-K) with neuropsychological functioning; to address interactions with the SWN-K domain mental functioning as a measure of subjective cognitive dysfunction; and to examine the interaction of subjective well-being and psychopathology ratings. Methods Forty-five patients diagnosed with schizophrenia spectrum disorder (SSD) were assessed regarding subjective well-being (SWN-K), neuropsychological impairment, and psychopathology (Brief Psychiatric Rating Scale; BPRS). Results After controlling for multiple comparisons, SWN-K total score showed significant positive correlations with concentration/attention (r =.498), working memory (r =.537), verbal memory (r =.522), and global cognition (r =.459). No correlations of SWN mental functioning and neuropsychological impairment remained significant after Bonferroni correction. Correlations between SWN-K subscales and neuropsychological functioning were generally positive, indicating higher subjective well-being in patients with better neurocognition. In multivariate analyses, global cognition was a significant predictor (p =.011), accounting for 19.7% of SWN total score variance. Adding BPRS total score as predictor (p =.054) explained an additional 6.9% of SWN-K variance. Linear regression analyses with SWN-K mental functioning as dependent variable did not yield statistically significant models. Conclusion Subjective well-being and objective neuropsychological functioning show only moderate associations and can be seen as largely independent parameters. In particular, subjective mental functioning cannot serve as a proxy for objective neuropsychological testing.
AB - Objective To assess the association of subjective quality of life as measured by the Subjective Well-being under Neuroleptic Treatment questionnaire (SWN-K) with neuropsychological functioning; to address interactions with the SWN-K domain mental functioning as a measure of subjective cognitive dysfunction; and to examine the interaction of subjective well-being and psychopathology ratings. Methods Forty-five patients diagnosed with schizophrenia spectrum disorder (SSD) were assessed regarding subjective well-being (SWN-K), neuropsychological impairment, and psychopathology (Brief Psychiatric Rating Scale; BPRS). Results After controlling for multiple comparisons, SWN-K total score showed significant positive correlations with concentration/attention (r =.498), working memory (r =.537), verbal memory (r =.522), and global cognition (r =.459). No correlations of SWN mental functioning and neuropsychological impairment remained significant after Bonferroni correction. Correlations between SWN-K subscales and neuropsychological functioning were generally positive, indicating higher subjective well-being in patients with better neurocognition. In multivariate analyses, global cognition was a significant predictor (p =.011), accounting for 19.7% of SWN total score variance. Adding BPRS total score as predictor (p =.054) explained an additional 6.9% of SWN-K variance. Linear regression analyses with SWN-K mental functioning as dependent variable did not yield statistically significant models. Conclusion Subjective well-being and objective neuropsychological functioning show only moderate associations and can be seen as largely independent parameters. In particular, subjective mental functioning cannot serve as a proxy for objective neuropsychological testing.
UR - http://www.scopus.com/inward/record.url?scp=84884349729&partnerID=8YFLogxK
U2 - 10.1016/j.comppsych.2013.02.008
DO - 10.1016/j.comppsych.2013.02.008
M3 - Article
C2 - 23602393
AN - SCOPUS:84884349729
SN - 0010-440X
VL - 54
SP - 824
EP - 830
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 7
ER -