Abstract
IgG4-related disease (IgG4-RD) is an inflammatory condition of unknown etiology that can cause tumefactive lesions in a number of tissues and organs, including the orbit and ocular adnexa. Diagnostic criteria for IgG4-RD, including pathology and clinical features and pathology, have been recently proposed.1 This study presents the first case of unilateral acute visual loss secondary to IgG4-related orbital inflammatory disease with orbital myositis that was complicated by severe compressive optic neuropathy. After initial treatment with pulsed intravenous methylprednisolone, followed by rituximab and radiotherapy, there was a marked improvement in orbital inflammation and clinical and radiological improvement in the compressive optic neuropathy. After 9 months of follow up, the orbital inflammatory disease remained in remission.
Original language | English |
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Pages (from-to) | e122-e125 |
Number of pages | 4 |
Journal | Ophthalmic Plastic and Reconstructive Surgery |
Volume | 30 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1 Feb 2014 |
Externally published | Yes |