TY - JOUR
T1 - Sugar metabolism by Brucellae
AU - Essenberg, Richard C.
AU - Seshadri, Rekha
AU - Nelson, Karen
AU - Paulsen, Ian
PY - 2002/12/20
Y1 - 2002/12/20
N2 - The metabolic capabilities of the species of Brucella were originally of interest as a means of distinguishing them from each other and from other genera. Certain unusual characteristics, especially erythritol utilization, were studied in the hopes they would shed light on the pathogenicity. With the advent of modern genetic methods and genomic sequencing, it is now possible to get a good idea of the total capabilities of the organism and to do tests to confirm these deductions. Brucella appears to be a fairly normal member of the α-proteobacteria, but with some differences. A few questions remain, such as whether Brucella uses the Entner-Doudoroff pathway. Some of the genes in carbohydrate utilization have been shown to be important in virulence.
AB - The metabolic capabilities of the species of Brucella were originally of interest as a means of distinguishing them from each other and from other genera. Certain unusual characteristics, especially erythritol utilization, were studied in the hopes they would shed light on the pathogenicity. With the advent of modern genetic methods and genomic sequencing, it is now possible to get a good idea of the total capabilities of the organism and to do tests to confirm these deductions. Brucella appears to be a fairly normal member of the α-proteobacteria, but with some differences. A few questions remain, such as whether Brucella uses the Entner-Doudoroff pathway. Some of the genes in carbohydrate utilization have been shown to be important in virulence.
KW - Brucella
KW - Erythritol
KW - Glucose
KW - Metabolism
KW - Sugars
UR - http://www.scopus.com/inward/record.url?scp=0037146622&partnerID=8YFLogxK
U2 - 10.1016/S0378-1135(02)00212-2
DO - 10.1016/S0378-1135(02)00212-2
M3 - Review article
C2 - 12414147
AN - SCOPUS:0037146622
SN - 0378-1135
VL - 90
SP - 249
EP - 261
JO - Veterinary Microbiology
JF - Veterinary Microbiology
IS - 1-4
ER -