Abstract
Single-molecule (SM) spectroscopy has been an exciting area of research offering significant promise and hope in the field of sensor development to detect targets at ultra-low levels down to SM resolution. To the experts and developers in the field of surface-enhanced Raman spectroscopy (SERS), this has often been a challenge and a significant opportunity for exploration. Needless to say, the opportunities and excitement of this multidisciplinary area impacts span the fields of physics, chemistry and engineering, along with a significant thrust in applications constituting areas in medicine, biology, environment and agriculture among others. In this review, we will attempt to provide a quick snapshot of the basics of SM-SERS, nanostructures and devices that can enable SM Raman measurement. We will conclude with a discussion on SERS implications in biomedical sciences.
Original language | English |
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Article number | 20120026 |
Pages (from-to) | 1-10 |
Number of pages | 10 |
Journal | Philosophical transactions of the Royal Society of London. Series B, Biological sciences |
Volume | 368 |
Issue number | 1611 |
DOIs | |
Publication status | Published - 5 Feb 2013 |
Externally published | Yes |
Keywords
- single molecule
- surface-enhanced Raman spectroscopy
- nanotechnology
- hot spot
- biological sciences