Sutureless and rapid-deployment aortic valve replacement international registry (SURD-IR)

early results from 3343 patients

Marco Di Eusanio, Kevin Phan, Paolo Berretta*, Thierry P. Carrel, Martin Andreas, Giuseppe Santarpino, Roberto Di Bartolomeo, Thierry Folliguet, Bart Meuris, Carmelo Mignosa, Gianluca Martinelli, Martin Misfeld, Mattia Glauber, Utz Kappert, Malak Shrestha, Alberto Albertini, Kevin Teoh, Emmanuel Villa, Tristan Yan, Marco Solinas

*Corresponding author for this work

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Objectives: The Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry (SURD-IR) was established by a consortium of 18 research centres - the International Valvular Surgery Study Group (IVSSG) - to overcome limitations of the literature and provide adequately powered evidence on sutureless and rapid-deployment aortic valves replacement (SURD-AVR). Methods: Data from 3343 patients undergoing SURD-AVR over a 10-year period (2007-2017) were collected in the registry. The mean age of the patients was 76.8 ± 6.7 years, with 36.4% being 80 years or older. The average logistic EuroSCORE was 11.3 ± 9.7%. Results: Isolated SURD-AVR was performed in 70.7% (n = 2362) of patients using full sternotomy (35.3%) or less invasive approaches (64.8%). Overall hospital mortality was 2.1%, being 1.4% in patients who had isolated SURD-AVR and 3.5% in those who had concomitant procedures (P < 0.001). When considering baseline risk profile, mortality rate was 0.8% and 1.9% in low risk (logistic EuroSCORE <10%) isolated SURD-AVR and combined SURD-AVR, respectively, and 2.2% and 3.7% in higher risk patients (logistic EuroSCORE ≥10%). Postoperative neurological complications included stroke (2.8%) and transient ischaemic attack (1.1%). New atrioventricular block requiring pacemaker occurred in 10.4% of the patients. The rate of pacemaker implantation significantly decreased over time [from 17.2% (2007-2008) to 5.4% (2016); P = 0.02]. Conclusions: Our findings showed that SURD-AVR is a safe and effective alternative to conventional aortic valve replacement and is associated with excellent clinical outcomes. Further adequately powered statistical analyses from the retrospective and prospective SURD-IR will allow for the development of high-quality evidence-based clinical guidelines for SURD-AVR.

Original languageEnglish
Pages (from-to)768-773
Number of pages6
JournalEuropean Journal of Cardio-thoracic Surgery
Volume54
Issue number4
DOIs
Publication statusPublished - 1 Oct 2018

    Fingerprint

Keywords

  • Aortic valve replacement
  • Rapid-deployment valve
  • Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry
  • Sutureless valve
  • The International Valvular Surgery Study Group

Cite this