TY - JOUR
T1 - Sutureless and rapid-deployment aortic valve replacement international registry (SURD-IR)
T2 - early results from 3343 patients
AU - Di Eusanio, Marco
AU - Phan, Kevin
AU - Berretta, Paolo
AU - Carrel, Thierry P.
AU - Andreas, Martin
AU - Santarpino, Giuseppe
AU - Di Bartolomeo, Roberto
AU - Folliguet, Thierry
AU - Meuris, Bart
AU - Mignosa, Carmelo
AU - Martinelli, Gianluca
AU - Misfeld, Martin
AU - Glauber, Mattia
AU - Kappert, Utz
AU - Shrestha, Malak
AU - Albertini, Alberto
AU - Teoh, Kevin
AU - Villa, Emmanuel
AU - Yan, Tristan
AU - Solinas, Marco
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Objectives: The Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry (SURD-IR) was established by a consortium of 18 research centres - the International Valvular Surgery Study Group (IVSSG) - to overcome limitations of the literature and provide adequately powered evidence on sutureless and rapid-deployment aortic valves replacement (SURD-AVR). Methods: Data from 3343 patients undergoing SURD-AVR over a 10-year period (2007-2017) were collected in the registry. The mean age of the patients was 76.8 ± 6.7 years, with 36.4% being 80 years or older. The average logistic EuroSCORE was 11.3 ± 9.7%. Results: Isolated SURD-AVR was performed in 70.7% (n = 2362) of patients using full sternotomy (35.3%) or less invasive approaches (64.8%). Overall hospital mortality was 2.1%, being 1.4% in patients who had isolated SURD-AVR and 3.5% in those who had concomitant procedures (P < 0.001). When considering baseline risk profile, mortality rate was 0.8% and 1.9% in low risk (logistic EuroSCORE <10%) isolated SURD-AVR and combined SURD-AVR, respectively, and 2.2% and 3.7% in higher risk patients (logistic EuroSCORE ≥10%). Postoperative neurological complications included stroke (2.8%) and transient ischaemic attack (1.1%). New atrioventricular block requiring pacemaker occurred in 10.4% of the patients. The rate of pacemaker implantation significantly decreased over time [from 17.2% (2007-2008) to 5.4% (2016); P = 0.02]. Conclusions: Our findings showed that SURD-AVR is a safe and effective alternative to conventional aortic valve replacement and is associated with excellent clinical outcomes. Further adequately powered statistical analyses from the retrospective and prospective SURD-IR will allow for the development of high-quality evidence-based clinical guidelines for SURD-AVR.
AB - Objectives: The Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry (SURD-IR) was established by a consortium of 18 research centres - the International Valvular Surgery Study Group (IVSSG) - to overcome limitations of the literature and provide adequately powered evidence on sutureless and rapid-deployment aortic valves replacement (SURD-AVR). Methods: Data from 3343 patients undergoing SURD-AVR over a 10-year period (2007-2017) were collected in the registry. The mean age of the patients was 76.8 ± 6.7 years, with 36.4% being 80 years or older. The average logistic EuroSCORE was 11.3 ± 9.7%. Results: Isolated SURD-AVR was performed in 70.7% (n = 2362) of patients using full sternotomy (35.3%) or less invasive approaches (64.8%). Overall hospital mortality was 2.1%, being 1.4% in patients who had isolated SURD-AVR and 3.5% in those who had concomitant procedures (P < 0.001). When considering baseline risk profile, mortality rate was 0.8% and 1.9% in low risk (logistic EuroSCORE <10%) isolated SURD-AVR and combined SURD-AVR, respectively, and 2.2% and 3.7% in higher risk patients (logistic EuroSCORE ≥10%). Postoperative neurological complications included stroke (2.8%) and transient ischaemic attack (1.1%). New atrioventricular block requiring pacemaker occurred in 10.4% of the patients. The rate of pacemaker implantation significantly decreased over time [from 17.2% (2007-2008) to 5.4% (2016); P = 0.02]. Conclusions: Our findings showed that SURD-AVR is a safe and effective alternative to conventional aortic valve replacement and is associated with excellent clinical outcomes. Further adequately powered statistical analyses from the retrospective and prospective SURD-IR will allow for the development of high-quality evidence-based clinical guidelines for SURD-AVR.
KW - Aortic valve replacement
KW - Rapid-deployment valve
KW - Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry
KW - Sutureless valve
KW - The International Valvular Surgery Study Group
UR - http://www.scopus.com/inward/record.url?scp=85053882563&partnerID=8YFLogxK
U2 - 10.1093/ejcts/ezy132
DO - 10.1093/ejcts/ezy132
M3 - Article
C2 - 29617925
AN - SCOPUS:85053882563
SN - 1010-7940
VL - 54
SP - 768
EP - 773
JO - European Journal of Cardio-thoracic Surgery
JF - European Journal of Cardio-thoracic Surgery
IS - 4
ER -