Syndactyly and intracranial arteriovenous malformation: case report

Lali H S Sekhon*, Michael K. Morgan, Ian H. Johnston

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A case of a 14-year-old boy with syndactyly of all limbs and intracranial dural arteriovenous malformation (AVM) is presented. A failure of differentiation of cerebral vessels, possibly at 3 weeks gestational age, is discussed along with several alternative theories relating to the pathogenesis of dural AVMs. The embryogenesis of syndactyly, occurring as an arrest of normal interdigital tissue regression at 5-7 weeks gestational age, is also reviewed. It is postulated that a single common intrauterine environmental insult of vascular origin occurring during the second month of gestation, is the reason for their simultaneous manifestation.

Original languageEnglish
Pages (from-to)377-380
Number of pages4
JournalBritish Journal of Neurosurgery
Issue number3
Publication statusPublished - 1994
Externally publishedYes


  • Arteriovenous
  • Development
  • Dural
  • Syndactyly


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