Synthesis of a new class of 5′-functionalized adenosines using a Rh(II)-catalyzed 1,3-dipolar cycloaddition

Fei Liu; David J. Austin

doi:10.1021/ol015995k

Synthesis of a new class of 5′-functionalized adenosines using a Rh(II)-catalyzed 1,3-dipolar cycloaddition

Fei Liu, David J. Austin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

(matrix presented) Chemically protected adenosine was functionalized at the 5′ position to generate novel dipolarophiles and mesoionic dipoles. These species were found to undergo facile 1,3-dipolar cycloaddition to afford a new series of adenosine derivatives that contain a point of diversification at the 5′ position of adenosine.

Original language	English
Pages (from-to)	2273-2276
Number of pages	4
Journal	Organic Letters
Volume	3
Issue number	15
DOIs	https://doi.org/10.1021/ol015995k
Publication status	Published - 26 Jul 2001
Externally published	Yes

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title = "Synthesis of a new class of 5′-functionalized adenosines using a Rh(II)-catalyzed 1,3-dipolar cycloaddition",

abstract = "(matrix presented) Chemically protected adenosine was functionalized at the 5′ position to generate novel dipolarophiles and mesoionic dipoles. These species were found to undergo facile 1,3-dipolar cycloaddition to afford a new series of adenosine derivatives that contain a point of diversification at the 5′ position of adenosine.",

author = "Fei Liu and Austin, {David J.}",

year = "2001",

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doi = "10.1021/ol015995k",

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T1 - Synthesis of a new class of 5′-functionalized adenosines using a Rh(II)-catalyzed 1,3-dipolar cycloaddition

AU - Liu, Fei

AU - Austin, David J.

PY - 2001/7/26

Y1 - 2001/7/26

N2 - (matrix presented) Chemically protected adenosine was functionalized at the 5′ position to generate novel dipolarophiles and mesoionic dipoles. These species were found to undergo facile 1,3-dipolar cycloaddition to afford a new series of adenosine derivatives that contain a point of diversification at the 5′ position of adenosine.

AB - (matrix presented) Chemically protected adenosine was functionalized at the 5′ position to generate novel dipolarophiles and mesoionic dipoles. These species were found to undergo facile 1,3-dipolar cycloaddition to afford a new series of adenosine derivatives that contain a point of diversification at the 5′ position of adenosine.

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U2 - 10.1021/ol015995k

DO - 10.1021/ol015995k

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AN - SCOPUS:0035954881

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VL - 3

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JO - Organic Letters

JF - Organic Letters

IS - 15

ER -

Synthesis of a new class of 5′-functionalized adenosines using a Rh(II)-catalyzed 1,3-dipolar cycloaddition

Abstract

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