Synthesis of some novel derivatives of 1,10-phenanthroline

Adel M. S. Garas, Robert S. Vagg

    Research output: Contribution to journalArticlepeer-review

    38 Citations (Scopus)

    Abstract

    The synthesis is described of a set of new N-heterocyclic compounds which are derivatives of 1,10-phenanthroline. The compounds are designed to be general purpose chelating agents which could function as tri-, tetra- or hexadentate ligands with transition metal ions. Fused-ring molecular components have been included in the design of the compounds so that they may function as binding agents to DNA through intercalation. This includes the synthesis of substituted derivatives of pyrazino[2,3-f][1,10]phenanthroline and dipyrido[3,2-a:2'3'-c]phenazine.

    Original languageEnglish
    Pages (from-to)151-158
    Number of pages8
    JournalJournal of Heterocyclic Chemistry
    Volume37
    Issue number1
    DOIs
    Publication statusPublished - 2000

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