Synthesis of stably deuteriated abscisic acid, phaseic acid and related compounds

R. D. Willows; A. G. Netting; B. V. Milborrow

doi:10.1016/0031-9422(91)84192-U

Synthesis of stably deuteriated abscisic acid, phaseic acid and related compounds

R. D. Willows, A. G. Netting, B. V. Milborrow^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Methyl esters of abscisic acid (ABA) analogues and metabolites dissolved in 0.1-1.0 M sodium methoxide in MeO²H replaced four of their sidechain ¹H atoms with ²H (C-4 and C-6) over a period of 4 to 8 weeks. The esters were hydrolysed by adding ²H₂O to provide ⁴H₄ labelled free acids. ABA, 1′,2′-epoxy-β-ionylidene acetic and phaseic acids have been labelled in this way. The method can be used to make ³H labelled materials.

Original language	English
Pages (from-to)	1483-1485
Number of pages	3
Journal	Phytochemistry
Volume	30
Issue number	5
DOIs	https://doi.org/10.1016/0031-9422(91)84192-U
Publication status	Published - 1991
Externally published	Yes

Keywords

Abscisic acid
deuteriation
internal standards
isomerization.
mass spectrometry
phaseic acid

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10.1016/0031-9422(91)84192-U

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title = "Synthesis of stably deuteriated abscisic acid, phaseic acid and related compounds",

abstract = "Methyl esters of abscisic acid (ABA) analogues and metabolites dissolved in 0.1-1.0 M sodium methoxide in MeO2H replaced four of their sidechain 1H atoms with 2H (C-4 and C-6) over a period of 4 to 8 weeks. The esters were hydrolysed by adding 2H2O to provide 4H4 labelled free acids. ABA, 1′,2′-epoxy-β-ionylidene acetic and phaseic acids have been labelled in this way. The method can be used to make 3H labelled materials.",

keywords = "Abscisic acid, deuteriation, internal standards, isomerization., mass spectrometry, phaseic acid",

author = "Willows, {R. D.} and Netting, {A. G.} and Milborrow, {B. V.}",

year = "1991",

doi = "10.1016/0031-9422(91)84192-U",

language = "English",

volume = "30",

pages = "1483--1485",

journal = "Phytochemistry",

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T1 - Synthesis of stably deuteriated abscisic acid, phaseic acid and related compounds

AU - Willows, R. D.

AU - Netting, A. G.

AU - Milborrow, B. V.

PY - 1991

Y1 - 1991

N2 - Methyl esters of abscisic acid (ABA) analogues and metabolites dissolved in 0.1-1.0 M sodium methoxide in MeO2H replaced four of their sidechain 1H atoms with 2H (C-4 and C-6) over a period of 4 to 8 weeks. The esters were hydrolysed by adding 2H2O to provide 4H4 labelled free acids. ABA, 1′,2′-epoxy-β-ionylidene acetic and phaseic acids have been labelled in this way. The method can be used to make 3H labelled materials.

AB - Methyl esters of abscisic acid (ABA) analogues and metabolites dissolved in 0.1-1.0 M sodium methoxide in MeO2H replaced four of their sidechain 1H atoms with 2H (C-4 and C-6) over a period of 4 to 8 weeks. The esters were hydrolysed by adding 2H2O to provide 4H4 labelled free acids. ABA, 1′,2′-epoxy-β-ionylidene acetic and phaseic acids have been labelled in this way. The method can be used to make 3H labelled materials.

KW - Abscisic acid

KW - deuteriation

KW - internal standards

KW - isomerization.

KW - mass spectrometry

KW - phaseic acid

UR - http://www.scopus.com/inward/record.url?scp=0000193107&partnerID=8YFLogxK

U2 - 10.1016/0031-9422(91)84192-U

DO - 10.1016/0031-9422(91)84192-U

M3 - Article

AN - SCOPUS:0000193107

SN - 0031-9422

VL - 30

SP - 1483

EP - 1485

JO - Phytochemistry

JF - Phytochemistry

IS - 5

ER -

Synthesis of stably deuteriated abscisic acid, phaseic acid and related compounds

Abstract

Keywords

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