Synthetic biology for the engineering of complex wine yeast communities

Roy S. K. Walker*, Isak S. Pretorius

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Wine fermentation is a representation of complex higher-order microbial interactions. Despite the beneficial properties that these communities bring to wine, their complexity poses challenges in predicting the nature and outcome of fermentation. Technological developments in synthetic biology enable the potential to engineer synthetic microbial communities for new purposes. Here we present the challenges and applications of engineered yeast communities in the context of a wine fermentation vessel, how this represents a model system to enable novel solutions for winemaking and introduce the concept of a ‘synthetic’ terroir. Furthermore, we introduce our vision for the application of control engineering.

Original languageEnglish
Pages (from-to)249-254
Number of pages6
JournalNature Food
Volume3
Issue number4
DOIs
Publication statusPublished - Apr 2022

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  • Centre of Excellence in Synthetic Biology

    Paulsen, I. (Primary Chief Investigator), Nevalainen, H. (Chief Investigator), Packer, N. (Chief Investigator), Scott, C. (Chief Investigator), Jackson , C. (Chief Investigator), Filipovska, A. (Chief Investigator), Rackham, O. (Chief Investigator), Alexandrov, K. (Chief Investigator), Lee, L. (Chief Investigator), Vickers, C. E. (Chief Investigator), Marcellin, E. (Chief Investigator) & Speight, R. (Chief Investigator)

    1/01/1831/12/18

    Project: Other

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