T2-weighted high-intensity signals in the basal ganglia as an interesting image finding in Unverricht-Lundborg disease

Miikka Korja*, Edoardo Ferlazzo, Merja Soilu-Hänninen, Adriana Magaudda, Reijo Marttila, Pierre Genton, Riitta Parkkola

*Corresponding author for this work

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    We conducted a search for white matter changes (WMCs) in 13 Unverricht-Lundborg disease patients and compared the prevalence of WMCs in these patients to age-matched long-term epileptics and healthy controls. ULD patients had significantly more T2-weighted high-intensity signals on MRI than control subjects, due to the increased prevalence of these signals in the basal ganglia. Interestingly, ULD patients with the basal ganglia changes were overweight. Basal ganglia T2-weighted high-intensity signals are novel findings in ULD.

    Original languageEnglish
    Pages (from-to)87-91
    Number of pages5
    JournalEpilepsy Research
    Volume88
    Issue number1
    DOIs
    Publication statusPublished - Jan 2010

    Keywords

    • Basal ganglia
    • T2-weighted
    • Unverricht-Lundborg disease
    • White matter changes

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