Tailored nanodiamonds for hyperpolarized 13C MRI

T. Boele, D. E. J. Waddington, T. Gaebel, E. Rej, Ajay Hasija, L. J. Brown, D. R. McCamey, D. J. Reilly

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)
    31 Downloads (Pure)


    Nanodiamond is poised to become an attractive material for hyperpolarized 13C magnetic resonance imaging if large nuclear polarizations can be achieved without the accompanying rapid spin-relaxation driven by paramagnetic species. Here we report enhanced and long-lived 13C polarization in synthetic nanodiamonds tailored by acid-cleaning and air-oxidation protocols. Our results separate the contributions of different paramagnetic species on the polarization behavior, identifying the importance of substitutional nitrogen defect centers in the nanodiamond core. These results are likely of use in the development of nanodiamond-based imaging agents with size distributions of relevance for examining biological processes.

    Original languageEnglish
    Article number155416
    Pages (from-to)1-11
    Number of pages11
    JournalPhysical Review B
    Issue number15
    Publication statusPublished - 15 Apr 2020

    Bibliographical note

    Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


    Dive into the research topics of 'Tailored nanodiamonds for hyperpolarized 13C MRI'. Together they form a unique fingerprint.

    Cite this