Targeting molecular mechanisms in cancer

Rosemary L. Balleine; Richard F. Kefford

doi:10.1046/j.1445-2197.2002.02470.x

Targeting molecular mechanisms in cancer

Rosemary L. Balleine^*, Richard F. Kefford

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Malignant disease is characterized by the disregulated growth of transformed cells. In recent years, dramatic insight into the molecular mechanisms of this phenomenon have come from basic cancer research. Detailed knowledge of the molecular pathology of cancer allows therapeutic agents to be designed that specifically target aberrant cellular processes. There are currently a number of targeted treatment strategies being evaluated. In the future, it is likely that this mechanistic approach will have a significant impact on clinical oncology and the diagnostic evaluation of tumours.

Original language	English
Pages (from-to)	760-763
Number of pages	4
Journal	ANZ Journal of Surgery
Volume	72
Issue number	10
DOIs	https://doi.org/10.1046/j.1445-2197.2002.02470.x
Publication status	Published - 2002
Externally published	Yes

Keywords

Molecular biology
Molecular oncology
Neoplasms

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10.1046/j.1445-2197.2002.02470.x

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title = "Targeting molecular mechanisms in cancer",

abstract = "Malignant disease is characterized by the disregulated growth of transformed cells. In recent years, dramatic insight into the molecular mechanisms of this phenomenon have come from basic cancer research. Detailed knowledge of the molecular pathology of cancer allows therapeutic agents to be designed that specifically target aberrant cellular processes. There are currently a number of targeted treatment strategies being evaluated. In the future, it is likely that this mechanistic approach will have a significant impact on clinical oncology and the diagnostic evaluation of tumours.",

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AU - Kefford, Richard F.

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AB - Malignant disease is characterized by the disregulated growth of transformed cells. In recent years, dramatic insight into the molecular mechanisms of this phenomenon have come from basic cancer research. Detailed knowledge of the molecular pathology of cancer allows therapeutic agents to be designed that specifically target aberrant cellular processes. There are currently a number of targeted treatment strategies being evaluated. In the future, it is likely that this mechanistic approach will have a significant impact on clinical oncology and the diagnostic evaluation of tumours.

KW - Molecular biology

KW - Molecular oncology

KW - Neoplasms

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U2 - 10.1046/j.1445-2197.2002.02470.x

DO - 10.1046/j.1445-2197.2002.02470.x

M3 - Review article

C2 - 12534393

AN - SCOPUS:0036428685

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EP - 763

JO - Australian and New Zealand Journal of Surgery

JF - Australian and New Zealand Journal of Surgery

SN - 1445-2197

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ER -

Targeting molecular mechanisms in cancer

Abstract

Keywords

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