TY - JOUR
T1 - Temporary abdominal closure
T2 - A prospective evaluation of its effects on renal and respiratory physiology
AU - Sugrue, Michael
AU - Jones, Felicity
AU - Janjua, Khan Jahangir
AU - Deane, Stephen A.
AU - Bristow, Peter
AU - Hillman, Ken
PY - 1998/11
Y1 - 1998/11
N2 - This study prospectively analyzed outcomes in 49 consecutive patients undergoing temporary abdominal closure (TAC) between 1993 and 1996 at a single university hospital. There were 37 males and 12 females, mean age was 57 years (range, 25-79 years), mean Acute Physiology and Chronic Health Evaluation score was 27 (±7.8 SD), and mean Simplified Acute Physiology II score was 53.0 (±15.4). The reason for TAC was decompression in 22 patients, inability to close the abdomen in 10 patients, to facilitate reexploration for sepsis in 8 patients, and multifactorial in 9 patients. After TAC, there was a significant reduction in intra-abdominal pressure from 24.2 ± 9.3 to 14.1 ± 5.5 mm Hg and improvement in lung dynamic compliance from 24.1 ± 7.9 to 27.6 ± 9.4 mL/cm H2O (p < 0.05). Although 10 patients experienced brisk diuresis, there was no significant improvement in renal function; in fact, serum creatinine increased. The median length of stay was 35 days (range, 1- 232 days). The mean number of abdominal operations after mesh insertion was 2.6 ± 2.4. There were 21 deaths, for a standardized mortality rate of 0.80. Although it achieved significant reductions in abdominal pressures and improved lung dynamic compliance, TAC did not result in improved renal function or patient oxygenation.
AB - This study prospectively analyzed outcomes in 49 consecutive patients undergoing temporary abdominal closure (TAC) between 1993 and 1996 at a single university hospital. There were 37 males and 12 females, mean age was 57 years (range, 25-79 years), mean Acute Physiology and Chronic Health Evaluation score was 27 (±7.8 SD), and mean Simplified Acute Physiology II score was 53.0 (±15.4). The reason for TAC was decompression in 22 patients, inability to close the abdomen in 10 patients, to facilitate reexploration for sepsis in 8 patients, and multifactorial in 9 patients. After TAC, there was a significant reduction in intra-abdominal pressure from 24.2 ± 9.3 to 14.1 ± 5.5 mm Hg and improvement in lung dynamic compliance from 24.1 ± 7.9 to 27.6 ± 9.4 mL/cm H2O (p < 0.05). Although 10 patients experienced brisk diuresis, there was no significant improvement in renal function; in fact, serum creatinine increased. The median length of stay was 35 days (range, 1- 232 days). The mean number of abdominal operations after mesh insertion was 2.6 ± 2.4. There were 21 deaths, for a standardized mortality rate of 0.80. Although it achieved significant reductions in abdominal pressures and improved lung dynamic compliance, TAC did not result in improved renal function or patient oxygenation.
UR - http://www.scopus.com/inward/record.url?scp=0031728179&partnerID=8YFLogxK
M3 - Article
C2 - 9820703
AN - SCOPUS:0031728179
SN - 1079-6061
VL - 45
SP - 914
EP - 921
JO - Journal of Trauma - Injury, Infection and Critical Care
JF - Journal of Trauma - Injury, Infection and Critical Care
IS - 5
ER -