Tetrapyrrole biosynthesis and signaling (chlorophyll, heme, and bilins)

Robert D. Willows, J. Clark Lagarias, Deqiang Duanmu

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

Chlamydomonas utilizes the cyclic tetrapyrroles chlorophyll, heme, siroheme, vitamin B12, and linear tetrapyrrole (bilin) metabolites as cofactors for photosynthetic light harvesting, electron transport, redox reactions, mitigating oxidative stress, and signaling. With the exception of vitamin B12, Chlamydomonas can synthesize and degrade all of these tetrapyrroles. In this chapter, we review what is currently known about how Chlamydomonas biosynthesizes and metabolizes tetrapyrroles, how these processes are regulated, and the various functions of tetrapyrroles in Chlamydomonas.

Original languageEnglish
Title of host publicationThe Chlamydomonas Sourcebook
Subtitle of host publicationVolume 2: Organellar and Metabolic Processes
EditorsArthur R. Grossman, Francis-Andre Wollman
Place of PublicationLondon
PublisherElsevier
Chapter21
Pages691-731
Number of pages41
Volume2
Edition3rd
ISBN (Electronic)9780128214305
ISBN (Print)9780323910583
DOIs
Publication statusPublished - 2023

Keywords

  • aminolevulinic acid
  • bilins
  • chlorophyll
  • ferrochelatase
  • Heme
  • heme oxygenase
  • magnesium chelatase
  • phyllobilins
  • siroheme

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